HER3 and EGFR cell membrane receptors forming complex, illustration - stock photo

Illustration of a human cell membrane (purple and orange) showing a human epidermal growth factor receptor 3 (HER3, blue) bound to an epidermal growth factor receptor (EGFR) molecule (light blue) which has been activated by epidermal growth factor (EGF, red). In healthy cells HER3 binds to any of three proteins in the EGFR family as part of cell signalling pathways which are key to cell proliferation, adhesion, survival and development. Dysregulation of this family of proteins is linked to cancer progression